Clinical Resource

Fertility after 35: What your GP wants you to know

Words by Dr Valerie Ademisoye
Image of a woman smiling with her two young sons whilst they eat ice cream

If you’re thinking about trying for a baby after the age of 35, you’re not alone. In fact, this trend is only increasing as more women are choosing to start or grow their families later in life.

As a GP, here’s what I usually discuss with patients planning to conceive after 35. Think of this as a guide to what’s in your control, when to seek help, and how to make informed choices. 

 

Why fertility after 35 looks different

Women are born with all the eggs they’ll ever have around 1-2 million. By puberty, this falls to about 300,000 and continues to decline. In our 30s, this drop accelerates and becomes more noticeable after 35. By 40, fertility is about half of what it was before 30. 

That said, many women in their late 30s and early 40s do conceive naturally. The key is having the right information and support. 

 

What your GP might recommend

If you go to see your GP to talk about conceiving after 35, here’s what you can expect to cover during your appointment: 

  • A review of your health
    Your GP will discuss your menstrual cycles, existing medical conditions and lifestyle. They may check your blood pressure, weight and arrange blood tests to rule out conditions that can affect your fertility, such as thyroid problems, abnormal hormone profile or diabetes. 
  • Cycle tracking advice
    Understanding when you are most fertile is key. Ovulation (when the ovary releases an egg to be fertilised by sperm) occurs roughly two weeks before your next period. However, at-home ovulation predictor kits are not usually recommended. This is because whilst they indicate you may be due to ovulate soon, they do not tell you exactly when you are due to ovulate meaning sexual intercourse may occur at the wrong time. The best advice is to have regular sexual intercourse every two to three days as sperm can live in the vagina for up to one week. 
  • Lifestyle guidance
    Nutrition, exercise, sleep, limiting alcohol intake and smoking matter more than we realise. They aren’t magic fixes, but they do help to support overall health and hormone balance.  
  • Realistic timelines
    After the age of 35, most GPs recommend coming back after six months of regular, unprotected sex for fertility testing.  

 

Understanding ovarian reserve

You may have heard of ovarian reserve testing. It estimates how many eggs are left and how ovaries might respond to treatment. The three main tests are: 

  • Follicle stimulating hormone (FSH)
    A hormone that is produced by the brain, that stimulates the growth of follicles, (pouches in ovaries) that contain eggs. Higher levels of FSH can indicate a lower level of ovarian reserve, although FSH levels can vary throughout your cycle.  
  • Anti-Müllerian hormone
    This is a measure of the number of growing follicles and is influenced by age, with lower levels occurring after 35.   
  • Antral follicle count 
    When an ultrasound, is used to count the number of small immature follicles in the ovaries. Again, this count is influenced by age as it sharply decreases after the age of 35. 

 

The takeaway message from ovarian reserve testing is mixed. A low ovarian reserve does not necessarily mean you cannot conceive – it just suggests you may have fewer eggs than average for your age. Equally, a normal result does not guarantee easy conception, and it does not predict exactly how quickly you’ll get pregnant. Ovarian reserve testing is just one piece of the fertility puzzle and is best interpreted with the guidance of a fertility specialist.  

 

Is fertility preservation for you?

Fertility preservation can be a useful option, if you are not quite ready to try for a baby now but you want to keep the door open for later. Options can include: 

  • Egg freezing. This involves stimulating the ovaries with hormones, to collect mature eggs to be frozen for later use. 
  • Embryo freezing. This follows the same process, but the eggs are then fertilised with sperm and frozen. 

 

Success rates vary and are influenced by the age at the time of egg collection (women over the age of 35 tend to produce less eggs) and the method of freezing the eggs or embryos. So ideally, fertility preservation should happen in your early 30s, but it’s still a choice worth exploring depending on your situation. 

 

When to seek medical advice 

Knowing when to seek support is important – you should see your GP sooner if you are over the age of 35 and: 

  • you’ve been trying for 6 months with no success, 
  • your menstrual cycles are irregular or you do not have periods, 
  • you have had pelvic surgery, endometriosis or pelvic inflammatory disease, as it can affect fertility,  
  • you are experiencing painful periods, pelvic pain or heavy bleeding, as these can point to underlying issues such as fibroids.  

 

Remember, fertility isn’t just about eggs. Male factors play a role in about 40% of couples struggling to conceive. Semen analysis testing is part of the initial work-up too. 

 

Looking after your wellbeing

Trying to conceive can feel like a job with timed sex, cycle apps and endless research. It can be stressful, which can take a toll. It is important to remember simple things like exercise, mindfulness or talking openly with your partner. If anxiety or low mood starts to develop, your GP is there to support your mental, as well as your physical, health. 

One thing that is often overlooked in conversations about fertility is emotional health.”

Key takeaways 

  • Fertility naturally declines after 35, but many women conceive at this age.
  • Your GP can help with health checks, lifestyle advice, and fertility tests.
  • Ovarian reserve tests (FSH, AMH, antral follicle count) can provide useful information but aren’t the full story.
  • Fertility preservation, like egg freezing, is an option worth exploring if you’re not ready yet.
  • Seek advice if you’ve tried for 6 months without success, have irregular cycles, or other risk factors.
  • Emotional wellbeing matters just as much – support is available.

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ABOUT THE AUTHOR

Image of Dr Valerie Ademisoye
Dr Valerie Ademisoye
Dr Valerie Ademisoye is a GP with a specialist interest in women’s health and menopause care.

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